Technologieangebote

Diacylglycerol kinase alpha as a epigenetic marker for developing fibrosis after radiotherapy

The invention reveals a method, based on metylation analysis of intragenic regions of the gene DGKA, for estimating the risk of developing radiation induced fibrosis and can therefore be used for therapy planning.

Device for sample purification by paramagnetic beads

The invention discloses a device that enables bead purification and mixing of the sample without the need for moving the reaction plate from one deck position to the other and hence saving time and deck space.

A natural rodent model system for papilloma-virus (PV) – induced cancer

The Mastomys mouse model is the only existing natural laboratory model to investigate PV pathogenesis and tumor development in the skin, ear, eye and tongue and could help to develop prophylactic or therapeutic approaches to prevent those lesions.

New synergistic effects of inhibition of Histone deacetylases 8 and 10 as well as ALK as treatment options in neuroblastoma.

The invention shows that a combination of HDAC and ALK inhibitors for tumortherapy is surprisingly synergistic and can additionally overcome single substance drug resistance.

Plasma S100P and hyaluronic acid level as prognostic and treatment monitoring markers for metastatic breast cancer

The present invention comprises the use of two serum/plasma markers for stage discrimination and prediction of survival as well as treatment response in breast cancer patients. Test statistics show that these markers outperform established ones like the number of circulating tumor cells (CTCs).

A Fast and Cost-Efficient In Vivo Model to Investigate Tumor Metastasis

The invention discloses an improved version of the chorionallantic membrane, for accurate quantification of metastatic cells in different organs of the chicken embryo at a high sensitivity.

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