Technologieangebote

The peptides identified by our inventors block the intracellular activity of the HPV16 E6 protein and thus increase sensitivity of tumor cells towards apoptosis. This effect is highly specific for HPV16-containing tumor cells.

Since cell culture contamination cannot be totally avoided, regular testing is a key factor for good cell culture management. The present invention provides means and methods to simultaneously detect up to 35 viral, microbial and inter-species contaminations. It facilitates sensitive and reliable determination of cell line purity. The technology is based on multiplex PCR and Luminex detection. Especially production units can profit from this cost-effective high-throughput method.

Method for the enrichment of diagnostic target molecules based on CD24 positive exosome purification, enabling the development of mainly cancer or fetal diagnostics and reducing false negative test results due to diluted diagnostic target molecules.

Metformin is a well-known anti-diabetic drug. The current technology offers the opportunity to use Metformin, as second medical use, for the treatment of multiple sclerosis and graft-versus-host disease.

DKFZ together with Technical University of Denmark (DTU) developed an analogue of Griseofulvin as a compound for cancer treatment, which selectively targets cancer cells only.

L1 is overexpressed in highly malignant carcinomas and human ovarian tumors. The antibody 9.3 has improved anti-tumor capacities by inhibit tumor growth and invasion of tumor cells. Antibody can be also used to determine the L1 level in a patient.