Technologieangebote

DKFZ together with Technical University of Denmark (DTU) developed an analogue of Griseofulvin as a compound for cancer treatment, which selectively targets cancer cells only.

L1 is overexpressed in highly malignant carcinomas and human ovarian tumors. The antibody 9.3 has improved anti-tumor capacities by inhibit tumor growth and invasion of tumor cells. Antibody can be also used to determine the L1 level in a patient.

“Ready to use kit” for simultaneous quantitative detection of up to 51 HPV genotypes. Kit contains internal quality and performance controls and allows identification of cervical abnormalities by predefined high viral load cutoffs.

Quadscanner for High Resolution Scanning Microscopes and Array Readers. The key facts are: (1) Fast, adaptive optical scanning device; (2) Completely free positioning of the scanning mirrors regarding the conjugated back focal plane; (3) Calibration with 4 galvanometers; (4) Application in high resolution microscopes (fluorescence, Raman, STED, localization), but also in Array Readers.

The technology specifies a novel device which allows to stabilize images of optical microscopes with high resolutions against externally induced oscillations and drift effects. In particular for optical microscopes, which achieve a higher resolution, it is important to ensure a high mechanical stability of the structure of microscope for a good image quality. It improves the performance of instruments such as laser scanners, fluorescence microscopes, Raman systems, STED- or localization-microscopes.

Optical techniques, such as bioluminescence and fluorescence, are emerging as powerful new modalities for molecular imaging in disease and therapy. Combining innovative molecular biology and chemistry, researchers have developed optical methods for imaging a variety of cellular and molecular processes in vivo, including protein interactions, protein degradation, and protease activity. DKFZ developed an optical imaging detector regarding fluorescence and bioluminescence for small animal imaging, which is compatible for magnetic resonance imaging (MRI). This technology provides the possibility to study simultaneously tracer/marker kinetics of optical (OT) as well as NMR induced signals.