Technologieangebote

The present invention is a technology that significantly simplifies the measurement of BAT by PCR-based quantification of exosomal microRNA-92a in serum. Exosomal miR-92a levels inversely correlate with BAT activity. This novel method is as the first of its kind qualified to routinely measure the BAT activity in large cohorts of patients.
The measurement of BAT activity is not only important in the diagnosis and treatment of weight-related diseases, but is also a screening tool for the development of drugs that regulate the BAT activity. Such drugs are of use in pathological leanness (e.g. cachexia), obesity and other metabolic diseases.
The invention has been validated by studies in mice and man. On behalf of the University of Bonn, PROvendis offers access to rights for commercial use as well as the opportunity for further co-development. In case of interest we will be pleased to inform you about the patent status.

The invention here described regards a textile rescue seat designed for the effective distribution of the weight on two carrying-operators. Experiments show that an adult of average weight can be carried on staircases and along corridors without overloading the two operators, relieving the strain on shoulders, neck and back and preventing health issues.
A prototype of the invention has been produced and successfully tested in a simulated evacuation in a multi-storey building. Low material and production costs comibined with little space required for storage are attractive features for a competitive product to be introduced into the market. Many items can be preventively stored in every public building or on board passenger ships and used also by non-professional operators. The principle of usage is intuitive and enables every healthy person on site to take part in the evacuation operation. A patent application has been filed in Germany. On behalf of the RWTH University, PROvendis is seeking a partner for further development in view of licensing the technology.

State of the art antimicrobial polymers are polymers with antimicrobial additives such as silver or copper. Additionally, a further approach is using functionalized monomers, containing amine or quaternary ammonium/phosphonium groups. These monomers can be polymerized to intrinsically microbial polymers. Unfortunately, they suffer from poor material properties (low glass transition temperature, high water uptake).
The novel intrinsic antimicrobial polymers overcome these shortcomings. Several groups of polymers have been developed (homopolymers and copolymers) with favorable processing characteristics, e.q. can be used in an injection molding process or press molding.
The standard JIS Z 2801 test to quantitatively test the ability to inhibit the growth of microorganisms over a 24 hour period of contact reveals a reduction of up to log 7,1.
Four patent applications have been filed at the European Patent Office. Further international applications are still possible. On behalf of the Fachhochschule Münster PROvendis offers licenses for interested enterprises.

Die Erfindung dient der Herstellung additiv gefertigter Bauteile aus amorphen, teilkristallinen oder auch kristallinen niedrigschmelzenden Metallen. Die Aufgabe der Erfindung wird mithilfe eines Extrusionsverfahrens gelöst. Das Ausgangsmaterial (Metallgranulat) wird über den Glasübergangsbereich, teilweise bis zur Schmelztemperatur erwärmt um damit in einen thermoplastischen Zustand zu gelangen. Anschließend kann unter Kraft-einwirkung die Schmelze extrudiert und selektiv auf eine Bauplattform aufgetragen werden. Die Erfindung ist dabei in der Lage, sowohl Hohlstrukturen als auch komplexe Bauteile mit guten mechanischen Eigenschaften zu fertigen. Durch die Frei-formgenerierung der Bauteile auf der Bauplattform entfallen in späteren Prozessschritten das Entfernen von ungebundenem Material sowie eine Reinigung des Bauraums.

Food industry is seeking for strategies to enhance production throughput in order to reduce costs. One bottleneck is not the production process itself, but the subsequent quality control analysis of each production charge. The herein described invention expedites this process and is therefore of interest for contract analytic labs as well as for food production companies with an own quality analysis laboratory. The culture medium has been optimized for osmo-tolerant yeast growth and has been tested and validated in comparison to conventional culture media. The invention is ready for industrial use.
On behalf of the University of Applied Sciences Ostwestfalen-Lippe, PROvendis offers access to rights for commercial use as well as the opportunity for further co-development. In case of interest we will be pleased to inform you about the patent status.

Die neue Technologie beinhaltet einen Deckel für Probenröhrchen (z. B. Kryoröhrchen), der mit einem Kanal für z. B. Thermoelemente ausgestattet sein soll und somit erstmalig definierte Messungen ermöglichen und gleichzeitig Kontaminationen verhindern kann. Der neuartige Deckel soll die Möglichkeit bieten, weitere Komponenten zu integrieren.