Variation analysis, risk pattern identification and target valdation

Genetic variation within a specific gene may influence the expression of this gene as well as the structure and function of the gene product.
This may lead to the predisposition to a specific disease or, if that gene encodes a drug target, this variation may result in largely different responses of particular individuals to a given drug.

GenProfile offers the identification and analysis of the interindividual genetic variation of specific genes, provided by the customer.
This service will include double stranded DNA sequencing of a defined number of DNA samples, and the application of bioinformatic tools.
GenProfile will use DNA samples provided by its customers. Also, the in-house DNA repository consisting of a large and phenotypically well characterized sample collection, generated with fully informed consent through GenProfile’s clinical network, will be accessable on request.